Identification of the Phytocomponents in Cymbopogon citratus Methanol Extract by Gas Chromatography-Mass Spectrometry

K. K Igwe; N .E. Udeh; A.J. Madubuike; S.C. Akomas; C. C. Amuneke

doi:10.17722/ijrbt.v8i2.264

Authors

K. K Igwe Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
N .E. Udeh Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
A.J. Madubuike Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
S.C. Akomas Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
C. C. Amuneke Departmemt of Veterinary Physiology, Pharmacology and Biochemistry, Michael Okpara University of Agriculture, Umudike, Nigeria

DOI:

https://doi.org/10.17722/ijrbt.v8i2.264

Keywords:

Dimercaprol, GCMS, Cymbopogon, citratus, Antioxidant

Abstract

Phytocomponents in methanolic extract of Cymbopogon citratus leaf was studied using GC MS analysis. 5 compounds were identified from the extract. The most abundant compounds were, Dimercaprolwith[ RT: 22.727, Peak area: 44.88 % and Molecular formula: C₃H₈OS₂]. Pentafluoropropanoyl with [RT: 21.942, Peak area: 34.16% and Molecular formula: C₁₄H₈F₁₀O₄ ] with an unknown bioactivity and Palmitic acid with [RT: 19.950, Peak area: 14.14 % and Molecular formula: C₁₆H₃₂O₂] which presented an antioxidant property. Other phytocompounds identified by GCMS but at different lower concentrations were 5-Chloropyrimidin-2-amin with [RT: 19.331, Peak area: 5.02 % and Molecular formula: C₄H₄CIN₃]and 3-Chloropyridin-2-ol with [RT: 18.375, Peak area: 1.80% and Molecular formula C₅H₄CINO]. The bioactive compounds in the methanol leaf extract of Cymbopogon citratus leaf demonstrated phytopharmacological action and hence could be of clinical use against some ailments.